Evidence synthesis at AI scale, delivered by experts
Synthesa helps CROs, medcomms agencies, pharma, medical device, BioTech and MedTech teams complete systematic reviews, abstract screening, meta-analyses, and rapid evidence synthesis faster, with expert validation at every step.
1,000,000+
abstracts screened
20,000+
outcomes meta-analysed
7 to 14 days
average project delivery
When the literature is too large, too complex, or too urgent for manual workflows
Synthesa is designed for projects where conventional approaches become slow, expensive, or impractical.
We support:
- Search strategy generation
- High-volume abstract screening
- Data extraction
- Risk of bias assessment
- Frequentist and Bayesian network meta-analyses
- Frequentist and Bayesian meta-regressions
- Frequentist and Bayesian meta-analyses
Whether you need to accelerate a live project, validate a prior review, or understand a complex evidence base quickly, Synthesa gives you expert-led evidence synthesis at scale.
Designed for evidence synthesis projects that exceed human-only capacity
Our AI-powered workflows allow us to screen very large literature sets, extract relevant data, and synthesise complex outcomes with speed and consistency.
- 1,000,000+ abstracts screened across evidence synthesis projects
- 20,000+ outcomes meta-analysed
- 7 to 14 day average project delivery compared with traditional timelines that often exceed 4 months
- 20% more relevant abstracts identified compared with human-only screening teams
- Peer-reviewed publications supporting our methodological and applied expertise
Start with a free abstract screening pilot
For many clients, the best way to evaluate Synthesa is to test our workflow on a clearly defined project.
We can run a free pilot using your defined search strategy and PICO criteria. The pilot can be conducted in parallel with your current human screening team or compared against a completed project.
What you receive
- Screening based on your search strategy and inclusion criteria
- A structured list of screened abstracts
- Transparent inclusion and exclusion decisions
- A comparison point against your internal or previous review process
- Delivery within a few days
CROs and medcomms agencies
Scale your evidence synthesis capacity without expanding your internal team. Synthesa supports abstract screening, data extraction, meta-analysis, and specialist evidence synthesis work for client projects, overflow needs, and tight timelines.
Pharma and medical affairs
Generate evidence for publication planning, medical strategy, internal decision-making, and evidence gap assessment with faster turnaround and expert-reviewed outputs.
Medical device companies
Identify, evaluate, and synthesise evidence to support medical, commercial, and market access objectives, especially where evidence is scattered across years of literature.
MedTech startups
Move quickly from scattered evidence to structured insight. Synthesa helps startups understand the existing evidence base, inform strategy, and support investor, partner, and commercial discussions.
Specialist evidence synthesis services
High-volume title and abstract screening based on defined criteria, supported by AI-powered workflows and expert oversight.
Structured evidence reviews for publication, medical strategy, market understanding, and decision support.
Comparative evidence synthesis across multiple interventions, including frequentist and Bayesian approaches.
Focused reviews for teams that need reliable evidence quickly for internal, strategic, or commercial decisions.
AI-powered workflow. Expert-led delivery. Clear outputs.
Step 1
Define the question
We align on the research objective, PICO criteria, search strategy, outcomes, timeline, and intended use of the outputs.
Step 2
Screen and extract at scale
Our AI-powered workflows accelerate screening and extraction while maintaining structured review logic and traceable decisions.
Step 3
Expert validation and analysis
Evidence synthesis specialists review outputs, resolve uncertainties, conduct statistical analyses where required, and prepare structured deliverables.
Step 4
Deliver decision-ready evidence
You receive clear, usable outputs, from screened abstract lists to full reviews, meta-analyses, network meta-analyses, and publication-ready evidence packages.
Case Studies:
Evidence synthesis delivered in weeks, not months
Medical device company
A medical affairs team needed to establish the evidence-based advantage of a device category using published literature instead of running a new clinical study. Synthesa completed screening, data extraction, and full meta-analysis in 2 weeks. The expected traditional timeline was 3 months.
Large-scale Bayesian meta-analysis
A research consortium investigating cardiac remodelling in pre-eclampsia needed to synthesise a large and complex evidence base. Synthesa screened 138,000 abstracts, extracted data from 75 relevant studies, and conducted Bayesian random-effects meta-analyses and meta-regressions in 3 weeks. The work was published in a peer-reviewed journal.
MedTech startup evidence review
A MedTech startup needed a fast, reliable overview of the literature to inform internal decision-making and establish its evidence base. Synthesa delivered a detailed literature review within 1 week.
Grounded in published scientific work
Synthesa’s team has contributed to peer-reviewed scientific publications across evidence synthesis, meta-analysis, medical research, and AI-enabled review workflows.
Our publication record supports how we work: structured methods, transparent synthesis, and expert interpretation.
For researchers who want to run their own meta-analysis
Synthesa is also developing Online Meta-Analysis AI, a self-service platform for researchers who already have their dataset ready and want to conduct a full statistical meta-analysis without statistics or programming expertise.
This product will be separate from our managed services and available through a dedicated subdomain.
Have an evidence synthesis project that needs speed, scale, and expert review?
Tell us what you are working on. We will help you assess the best route: a free abstract screening pilot, a rapid evidence synthesis project, or a full systematic review and meta-analysis.